|  Vineet Gupta is a person living in Miami lakes, Florida. He is also CoDirector of the Peggy and Harold Katz Family Kidney Drug Discovery Center. Open Full Report. Jhansen Reinoso is a resident of Hialeah. Vineet Gupta of the University of Miami in the U.S. will develop a computational model to identify new DNA sequences in the Tuberculosis bacterium that can be used as biomarkers, and then employ zinc-finger tags to detect the identified DNA sequence in a diagnostic test. Invest. Financial Support This study was funded by NIH grants R01-CA170946 and R01-CA124723 (to AKS); NIH grant R01-CA184274 (to SB); Katherine and Robert Goodale foundation support (to AKS), Minneamrita Therapeutics LLC (to AKS). Location - Miami lakes, Florida. This site needs JavaScript to work properly. Lookup the home address and phone and other contact details for this person. There are 50 individuals that go by the name of Vineet Gupta. MiRNA-Mediated Macrophage Polarization and its Potential Role in the Regulation of Inflammatory Response. Vineet Gupta is a resident of FL. Norristown, Pennsylvania. 2020 Oct 14;9(10):giaa109. Reprint of Neutrophil cell surface receptors and their intracellular signal transduction pathways. Immunity. CD11b suppresses PDGF-BB-dependent neovascularization and tumor growth. UHealth is now offering COVID-19 vaccine appointments to our patients age 65 and older with CDC approved risk criteria.We are contacting all eligible patients to … Int J Mol Sci. -, Cotechini T, Medler TR, Coussens LM. In contrast, inhibition of CD11b prevents Let7a expression and induces cMyc expression, leading to immune suppressive macrophage polarization, vascular maturation, and accelerated tumor growth. Here we report that, unexpectedly, integrin CD11b does not regulate myeloid cell recruitment to tumors but instead controls myeloid cell polarization and tumor growth. 2015;21:343–350. Looking for Vineet Gupta? Vineet has 8 jobs listed on their profile. eCollection 2019. a CD31, Desmin, NG2, Smooth muscle…, CD11b promotes miR- Let7a mediated immune stimulation. Vineet Gupta is a practicing Internal Medicine doctor in San Diego, CA doi: 10.1038/nm.3394. Check Reputation. Enter multiple addresses on separate lines or separate them with commas. Works at. Vinest Gupta in Miami, FL We found Vinest Gupta in Miami - select Vinest below based on age, prior locations, and family. Yao X, Dong G, Zhu Y, Yan F, Zhang H, Ma Q, Fu X, Li X, Zhang Q, Zhang J, Shi H, Ning Z, Dai J, Li Z, Li C, Wang B, Ming J, Yang Y, Hong F, Meng X, Xiong H, Si C. Front Immunol. The remaining authors declare no competing interests. Integrin CD11b agonism suppresses tumor growth and promotes survival in mouse models of cancer. Vineet Gupta is the Founder and CEO of 149 Bio. 6 DeWitt Daughtry Family Department of Surgery, Leonard M. Miller School of Medicine, University of Miami, Miami, FL 33136; vineet_gupta@rush.edu rvazquez@med.miami.edu. 2012;4:14. doi: 10.1186/2045-824X-4-14. 2016 Sep;185(3):361-71. doi: 10.1111/cei.12803. SB is a consultant with Minneamrita Therapeutics LLC and this relationship is managed by University of Miami. See more stories about Wreck, Miami Beach, FL. [The activation of CD11b by leukadherin-1 alleviates endotoxic shock through promoting the aggregation and activation of myeloid-derived suppressor cells]. Vasc. Dr. doi: 10.1172/JCI59643. Nat. Vineet Gupta, PhD Principal Investigator I received my MS in Chemistry from IIT Delhi and my PhD in Chemistry from University of Rochester in Rochester, NY. The aggressive biology of the disease is responsible for such dismal outcome and is manifested by an increase in self-renewal capacity of the cancer cells, which leads to an increased rate of tumor-recurrence, contributing to poor prognosis. The authors would also like to acknowledge Oncogenomics Core at the Sylvester Cancer Center, University of Miami for their help with the RNA seq transcriptomics study. Vineet Kumar Gupta Post Doctoral Fellow at Dept. Epub 2016 Jul 26. Dr. Gupta graduated from the University College of Medical Sciences,University College of Medical Sciences and Guru Teg Bahadur Hospital in 1990. Conflict of interest University of Minnesota has a patent for Minnelide, which has been licensed to Minneamrita Therapeutics, LLC. Next . Add Info + Vineet Gupta. (Page 3) Vineet Gupta is founder of Adhaere Pharmaceuticals, a biotechnology company developing LA1 for therapeutic indications. Find more results for Vineet Gupta. Vineet Gupta Locations Include: We could uncover more information on Vineet at any time - we update our databases every 24 hours! Cell. No reuse allowed without permission. This activates Sox2 transcriptional activity by stabilizing the protein in the nucleus. We found records in 27 states. CD47 Ligation Repositions the Inhibitory Receptor SIRPA to Suppress Integrin Activation and Phagocytosis. J. Clin. In cancer, SOX2 is aberrantly “turned-on” leading to activation of self-renewal pathways in cancer. Nikita S. Sharma, Vineet K. Gupta, Roey Hadad, Bhuwan Giri, Anthony Ferrantella, Vikas Dudeja, Ashok K. Saluja and Sulagna Banerjee Cancer Immunol Res April 1 2020 (8) (4 Supplement) A59; DOI: 10.1158/2326-6074.TUMIMM18-A59 National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. See Vineet's age, contact number, house address, email address, public records & run a background check. Thank you for your interest in spreading the word about bioRxiv. Whitepages people search is the most trusted directory. Our study also demonstrated that targeting OGT in vivo with a small molecule inhibitor OSMI, results in decreased tumor burden, delayed tumor progression and a decreased expression of SOX2 in pancreatic cancer cells. People Search, Background Checks, … Myeloid cells in tumor inflammation. Candas-Green D, Xie B, Huang J, Fan M, Wang A, Menaa C, Zhang Y, Zhang L, Jing D, Azghadi S, Zhou W, Liu L, Jiang N, Li T, Gao T, Sweeney C, Shen R, Lin TY, Pan CX, Ozpiskin OM, Woloschak G, Grdina DJ, Vaughan AT, Wang JM, Xia S, Monjazeb AM, Murphy WJ, Sun LQ, Chen HW, Lam KS, Weichselbaum RR, Li JJ. Vineet Gupta in Massachusetts. 90 records for Vineet Gupta. Phone Number (612) 413-**** Unlock Phone Number. Not the person you're looking for? Microenvironmental regulation of tumor progression and metastasis. Roberts AL, Fürnrohr BG, Vyse TJ, Rhodes B. Clin Exp Immunol. Significance Our study highlights for the first time that that the O-GlcNAc transferase dependent SOX2 glycosylation determines self-renewal in pancreatic cancer which is responsible for tumor initiation. The remaining authors declare no conflict of interest. R01 CA083133/CA/NCI NIH HHS/United States, R01 CA167426/CA/NCI NIH HHS/United States, P30 CA023100/CA/NCI NIH HHS/United States, K99 HL112962/HL/NHLBI NIH HHS/United States, Quail DF, Joyce JA. Shock. The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. 41 year old . 2020 Sep 14;11(1):4591. doi: 10.1038/s41467-020-18245-7. Dr. Myeloid cells are recruited to damaged tissues where they can resolve infections and tumor growth or stimulate wound healing and tumor progression. 2019 Feb 12;10:215. doi: 10.3389/fimmu.2019.00215. Job Title. Int Immunopharmacol. AKS is the co-founder and the Chief Scientific Officer of this company. Explore Vineet Gupta's magazine "Smart City", followed by 752 people on Flipboard. View phone numbers, addresses, public records, background check reports and possible arrest records for Vineet Gupta in Florida (FL). Transcription factor SOX2 maintains a critical balance between differentiation and “stemness” and is thus tightly regulated within a cell. Location of This Business 4960 NW 165th St Unit B20, Miami Lakes, FL 33014-6322 Email this Business 5Department of Surgery, University of Miami Leonard M. Miller School of Medicine, Miami 33136, USA. Vineet Gupta; People Search Results for Vineet Gupta Profile; Phone; Address; Email; Birthday; We found 97 people that match in the United States. Nat Commun. -, Schmid MC, Varner JA. Regulation of Sox2 in cancer is poorly understood. Location. a – f Relative mRNA expression of…, CD11b suppresses PDGF-BB-dependent neovascularization and…, CD11b suppresses PDGF-BB-dependent neovascularization and tumor growth. Click on the View Details button for more information. 2016 Aug;46(2):122-31. doi: 10.1097/SHK.0000000000000604. HHS Vineet is a successful entrepreneur and has taken two startups from concept to exit. Zaki3, Vineet Gupta1,2* 1Nephrology Division, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America, 2Division of Nephrology and Hypertension, Department of Medicine, University of Miami, Miami, Florida, United States of America, 3Department of Computer Science, Rensselaer Polytechnic Institute, FREE Background Report. Res. 6 Drug Discovery Center, Department of Internal Medicine, Rush University Medical Center, Chicago, IL, 60612, USA. O-GlcNAc modification of oncogenic transcription factor Sox2 promotes protein stability and regulates self-renewal in pancreatic cancer, Department of Surgery, University of Miami, Department of Pharmacology, University of Minnesota, Department of Psychology, Harvard University, School of Medicine Dean’s Office, University of Alabama at Birmingham. Would you like email updates of new search results? Myeloid cells as targets for therapy in solid tumors. doi: 10.1093/gigascience/giaa109. Vineet Gupta has lived in Norristown, PA 19403 . Check Reputation Score for Vineet Gupta in Pembroke Pines, FL - View Criminal & Court Records | Photos | Address, Emails & Phone Number | Personal Review | $150 - … a Relative mRNA expression of pro-inflammatory…, Macrophage microRNA let-7a is required…, Macrophage microRNA let-7a is required for tumor growth suppression. Vineet Gupta 2 & Judith A. Varner1,3 ... Miami, FL 33136, USA. A map of tumor-host interactions in glioma at single-cell resolution. Vineet Gupta, PhD is an Assistant Professor in Medicine in the Division of Nephrology and Hypertension, Department of Medicine at the Miller School of Medicine, University of Miami. CD11b ligation promotes pro-inflammatory macrophage signaling. 2 Web Editor, Science Signaling, American Association for the Advancement of Science, 1200 New York Avenue, NW, Washington, DC 20005, USA. He is also CoDirector of the Peggy and Harold Katz Family Kidney Drug Discovery Center. Yao X, Dong G, Zhu Y, Yan F, Zhang H, Dai J, Li X, Xiong H, Si C. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. doi: 10.1016/j.immuni.2020.07.008. These authors contributed equally: Michael C. Schmid, Samia Q. Khan, Megan M. Kaneda, Vineet Gupta, Judith A. Varner. They have also lived in Minneapolis, MN and Pinecrest, FL. 2017;5:3–8. He is also The Charles Weaver Chair for Cancer Research Professor and Vice Chair for Innovation in the Department of Internal Medicine at Rush University Medical Center, Chicago, IL. CD11b Signaling Prevents Chondrocyte Mineralization and Attenuates the Severity of Osteoarthritis. Overview. These studies identify CD11b as negative regulator of immune suppression and a target for cancer immune therapy. a , b Endothelial…, Integrin CD11b agonism suppresses tumor growth and promotes survival in mouse models of…, NLM Phone Number Epub 2020 Aug 7. USA.gov. 2020 Dec 18;8:611757. doi: 10.3389/fcell.2020.611757. 2018. TRADE ONE Click To Reveal. Conflict of interest University of Minnesota has a patent for Minnelide, which has been licensed to Minneamrita Therapeutics, LLC. Find Vineet Gupta's phone number, address, and email on Spokeo, the leading people search directory for contact information and public records. Caruso FP, Garofano L, D'Angelo F, Yu K, Tang F, Yuan J, Zhang J, Cerulo L, Pagnotta SM, Bedognetti D, Sims PA, Suvà M, Su XD, Lasorella A, Iavarone A, Ceccarelli M. Gigascience. LinkedIn is the world’s largest business network, helping professionals like Vineet Gupta discover inside connections to recommended job candidates, industry experts, and business partners. About Vineet Gupta. 2020 Aug 18;53(2):290-302.e6. of Surgery, University of Miami Miami, Florida 370 connections eCollection 2020. This question is for testing whether or not you are a human visitor and to prevent automated spam submissions. Our study highlights for the first time that that the O-GlcNAc transferase dependent SOX2 glycosylation has a profound effect on the transcriptional activity of SOX2 and is instrumental in determining self-renewal in pancreatic cancer. 2013;19:1423–1437. Get the latest public health information from CDC: https://www.coronavirus.gov, Get the latest research information from NIH: https://www.nih.gov/coronavirus, Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. 2020 Oct 19;21(20):7716. doi: 10.3390/ijms21207716. These individuals collectively are associated with 8 companies in 9 cities. Ehirchiou D, Bernabei I, Chobaz V, Castelblanco M, Hügle T, So A, Zhang L, Busso N, Nasi S. Front Cell Dev Biol. Recruitment of these cells is regulated by integrins, a family of adhesion receptors that includes integrin CD11b. 2018 Nov;34(11):961-968. The complement receptor 3 (CD11b/CD18) agonist Leukadherin-1 suppresses human innate inflammatory signalling.  |  We further showed that mutation of this site (S246A) prevents the modification of Sox2 and its downstream activity. His postdoctoral training in biomedical research and structural biology was at the Rockefeller University in New York City and at Massachusetts General Hospital, Harvard Medical School. See this image and copyright information in PMC. Cancer Immunol. doi: 10.1158/2326-6066.CIR-16-0297. doi: 10.1097/PPO.0000000000000132. Vineet Kumar Gupta has lived in Miami, FL, in zip codes 33145 and 33156; Minneapolis, MN 55414 . The third result is Vineet Gupta age --in Miami, FL in the Shenandoah neighborhood. -. NIH Pharmacological activation of CD11b with a small molecule agonist, Leukadherin 1 (LA1), promotes pro-inflammatory macrophage polarization and suppresses tumor growth in animal models of murine and human cancer. 2012;122:787–795. COVID-19 is an emerging, rapidly evolving situation. CD11b ligation promotes pro-inflammatory macrophage…, CD11b ligation promotes pro-inflammatory macrophage signaling. All rights reserved. Clipboard, Search History, and several other advanced features are temporarily unavailable. Select this result to view Vineet Gupta's … vineet_gupta@rush.edu. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. Vineet Gupta, PhD is an Assistant Professor in Medicine in the Division of Nephrology and Hypertension, Department of Medicine at the Miller School of Medicine, University of Miami. Cancer J. 5 Department of Surgery, University of Miami Leonard M. Miller School of Medicine, Miami, 33136, USA. -, Sica A, Mantovani A. Macrophage plasticity and polarization: in vivo veritas. CD11b activation promotes pro-inflammatory macrophage polarization by stimulating expression of microRNA Let7a. The cities are Brampton ON, Centreville VA, Coral Springs FL, Dallas TX, Glenview IL, Katy TX, Los Angeles CA, Louisville KY, Miami FL, Mississauga ON, Palm Harbor FL, Pembroke Pines FL, Pinellas Park FL, Plantation FL, Toronto ON, Upper Saddle River NJ, and … Company - TRADE ONE Click To Reveal. Vineet Gupta, PhD Principal investigator and lab head Gupta received his MS in chemistry from IIT Delhi and his PhD in Chemistry from the University of Rochester in Rochester, NY. A CRISPR-OGT knockout in pancreatic cancer cell line S2VP10 resulted in a delayed tumor initiation. ‪Professor of Medicine, Rush University Medical Center‬ - ‪Cited by 3,630‬ - ‪drug discovery‬ - ‪inflammation‬ - ‪integrin‬ - ‪kidney disease‬ Vineet Gupta in New York We found 15 results for Vineet Gupta in Brooklyn, Buffalo, and 20 other New York cities. There are 8 individuals that go by the name of Vineet Gupta in Florida. View Vineet Gupta’s professional profile on LinkedIn. My post-doctoral training in Biomedical Research and Structural Biology was at the Rockefeller University in New York City and at Massachusetts General Hospital, Harvard Medical School. Leukadherin-1-Mediated Activation of CD11b Inhibits LPS-Induced Pro-inflammatory Response in Macrophages and Protects Mice Against Endotoxic Shock by Blocking LPS-TLR4 Interaction. NOTE: Your email address is requested solely to identify you as the sender of this article.  |  People Search, Background Checks, Criminal Records, Contact Information, Public … Pancreatic cancer is among the 3rd leading cause of cancer related deaths in the United States along with a 5-year survival rate of 7%. Phone - (305) 620-2006 Click To Reveal. Vineet Gupta 1 and ; Annalisa M. VanHook 2; 1 Division of Nephrology and Hypertension, Department of Medicine, and Department of Biochemistry and Molecular Biology, University of Miami, Miami, FL 33136, USA. The cities are Hialeah, Miami, Oldsmar, Palm Harbor, Palmetto Bay, Pembroke Pines, Pinellas Park, Plantation, and Wesley Chapel. Myeloid-derived suppressor cells. These individuals collectively are associated with 44 companies in 17 cities. Nikita S Sharma, Vineet K Gupta, Patricia Dauer, Kousik Kesh, Roey Hadad, Bhuwan Giri, ... University of Miami for their help with the RNA seq transcriptomics study. 2013 Dec;17(4):1185-97. doi: 10.1016/j.intimp.2013.11.010. View Vineet Gupta’s profile on LinkedIn, the world’s largest professional community. Bidirectional Tumor-Promoting Activities of Macrophage Ezrin. ... FL 33014 is the current address for Vineet. Find Vineet Gupta's phone number, address, and email on Spokeo, the leading online directory for contact information. Epub 2013 Nov 18. Please enable it to take advantage of the complete set of features! Med. In the current study, we show for the first time that in pancreatic cancer, Sox2 is modified by addition of O-GlcNAc moiety, catalyzed by OGT (O-GlcNAc Transferase) at S246. -, Gabrilovich DI. The expected price of renting a two bedrooms in the 33014 zip code is $1,730/month. Dual blockade of CD47 and HER2 eliminates radioresistant breast cancer cells.